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Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol

Translocation of ricin A chain to the cytosol has been proposed to take place from the endoplasmic reticulum (ER), but attempts to visualize ricin in this organelle have failed. Here we modified ricin A chain to contain a tyrosine sulfation site alone or in combination with N-glycosylation sites. Wh...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Rapak, Andrzej, Falnes, Pål Ø., Olsnes, Sjur
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1997
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20518/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108055/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3783
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