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Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats.

Fimbrial production by Porphyromonas gingivalis was inactivated by insertion-duplication mutagenesis, using the cloned gene for the P. gingivalis major fimbrial subunit protein, fimA. by several criteria, this insertion mutation rendered P. gingivalis unable to produce fimbrilin or an intact fimbria...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Bacteriol
Prif Awduron: Malek, R, Fisher, J G, Caleca, A, Stinson, M, van Oss, C J, Lee, J Y, Cho, M I, Genco, R J, Evans, R T, Dyer, D W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8106316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.4.1052-1059.1994
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