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Mechanisms of endothelin-1-induced decrease in contractility in adult mouse ventricular myocytes
BACKGROUND AND PURPOSE: The potent vasoconstrictor polypeptide endothelin-1 (ET-1) plays an important pathophysiological role in progression of cardiovascular diseases and elicits prominent effects on myocardial contractility. Although ET-1 produces a positive inotropy in cardiac muscle of most mamm...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2050817/ https://ncbi.nlm.nih.gov/pubmed/17641672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707392 |
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