Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb–MuvB/dREAM complex in proliferating cells

Myb–MuvB (MMB)/dREAM is a nine-subunit complex first described in Drosophila as a repressor of transcription, dependent on E2F2 and the RBFs. Myb, an integral member of MMB, curiously plays no role in the silencing of the test genes previously analyzed. Moreover, Myb plays an activating role in DNA...

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Main Authors: Georlette, Daphne, Ahn, Soyeon, MacAlpine, David M., Cheung, Evelyn, Lewis, Peter W., Beall, Eileen L., Bell, Stephen P., Speed, Terry, Manak, J. Robert, Botchan, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049191/
https://ncbi.nlm.nih.gov/pubmed/17978103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1600107
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