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Alternative promoters and repetitive DNA elements define the species-dependent tissue-specific expression of the FMO1 genes of human and mouse

In humans, expression of the FMO1 (flavin-containing mono-oxygenase 1) gene is silenced postnatally in liver, but not kidney. In adult mouse, however, the gene is active in both tissues. We investigated the basis of this species-dependent tissue-specific transcription of FMO1. Our results indicate t...

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Detalhes bibliográficos
Main Authors: Shephard, Elizabeth A., Chandan, Pritpal, Stevanovic-Walker, Milena, Edwards, Mina, Phillips, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049042/
https://ncbi.nlm.nih.gov/pubmed/17547558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070523
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