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Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor

In the present study, we demonstrate that AC5 (type V adenylate cyclase) interacts with Ric8a through directly interacting at its N-terminus. Ric8a was shown to be a GEF (guanine nucleotide exchange factor) for several α subunits of heterotrimeric GTP binding proteins (Gα proteins) in vitro. Selecti...

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Detalhes bibliográficos
Main Authors: Wang, Shyi-Chyi, Lai, Hsing-Lin, Chiu, Yi-Ting, Ou, Ren, Huang, Chuen-Lin, Chern, Yijuang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049038/
https://ncbi.nlm.nih.gov/pubmed/17593019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070512
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