Structural and functional differences among human surfactant proteins SP-A1, SP-A2 and co-expressed SP-A1/SP-A2: role of supratrimeric oligomerization

SP-A (surfactant protein A) is a membrane-associated SP that helps to maintain the lung in a sterile and non-inflamed state. Unlike SP-As from other mammalian species, human SP-A consists of two functional gene products: SP-A1 and SP-A2. In all the functions examined, recombinant human SP-A1 invaria...

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Detalhes bibliográficos
Main Authors: Sánchez-Barbero, Fernando, Rivas, Germán, Steinhilber, Wolfram, Casals, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049033/
https://ncbi.nlm.nih.gov/pubmed/17542781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070275
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