Lymphocyte-Dependent and Th2 Cytokine-Associated Colitis in Mice Deficient in Wiskott-Aldrich Syndrome Protein

BACKGROUND & AIMS: Controversy exists as to whether patients with inflammatory bowel disease have an underlying immunodeficiency. We have focused on a murine model of the Wiskott-Aldrich syndrome, an immunodeficiency in which autoimmunity can manifest in the form of an inflammatory bowel disease...

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Autores principales: Nguyen, Deanna D., Maillard, Michel H., Cotta-de-Almeida, Vinicius, Mizoguchi, Emiko, Klein, Christoph, Fuss, Ivan, Nagler, Cathryn, Mizoguchi, Atsushi, Bhan, Atul K., Snapper, Scott B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048975/
https://ncbi.nlm.nih.gov/pubmed/17764675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.07.010
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