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B5 deficient vaccinia virus as a vaccine vector for the expression of a foreign antigen in vaccinia immune animals

Recombinant vaccinia viruses have shown promise as vaccine vectors. However, their effectiveness is markedly reduced by pre-existing anti-vaccinia immunity. The possibility of new vaccinia immunizations in the event of a bioterror-related smallpox release poses an additional negative impact on the u...

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Main Authors: Viner, Kendra M., Girgis, Natasha, Kwak, Heesun, Isaacs, Stuart N.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048764/
https://ncbi.nlm.nih.gov/pubmed/17188733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.11.020
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