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The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin

Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast protein Epe1 stabilises silent chromatin, preventing the oscillation of heterochromatin domains. Epe1 loss leads to two contrasting phenotypes: alleviation o...

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Detalhes bibliográficos
Main Authors: Trewick, Sarah C, Minc, Elsa, Antonelli, Richard, Urano, Takeshi, Allshire, Robin C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048757/
https://ncbi.nlm.nih.gov/pubmed/17948055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601892
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