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THE HUMAN–SHEEP CHIMERAS AS A MODEL FOR HUMAN STEM CELL MOBILIZATION AND EVALUATION OF HEMATOPOIETIC GRAFTS’ POTENTIAL

OBJECTIVE: To investigate whether the sheep xenograft model of human hematopoiesis can be used to mimic mobilization of human hematopoietic stem cells in vivo. MATERIAL AND METHODS: Sheep transplanted with 3.6×10(6) CD34(+) from human adult bone marrow were mobilized 1.5 years post-transplant with h...

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Main Authors: Almeida-Porada, Graça, Porada, Christopher, Gupta, Nicole, Torabi, Ali, Thain, David, Zanjani, Esmail D.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048750/
https://ncbi.nlm.nih.gov/pubmed/17889724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2007.07.009
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