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Metabolic flux analysis in a nonstationary system: Fed-batch fermentation of a high yielding strain of E. coli producing 1,3-propanediol

Metabolic fluxes estimated from stable-isotope studies provide a key to understanding cell physiology and regulation of metabolism. A limitation of the classical method for metabolic flux analysis (MFA) is the requirement for isotopic steady state. To extend the scope of flux determination from stat...

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Autors principals: Antoniewicz, Maciek R., Kraynie, David F., Laffend, Lisa A., González-Lergier, Joanna, Kelleher, Joanne K., Stephanopoulos, Gregory
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048574/
https://ncbi.nlm.nih.gov/pubmed/17400499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2007.01.003
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