Atomoxetine pharmacokinetics in healthy Chinese subjects and effect of the CYP2D6*10 allele

AIMS: To characterize atomoxetine pharmacokinetics, explore the effect of the homozygous CYP2D6*10 genotype on atomoxetine pharmacokinetics and evaluate the tolerability of atomoxetine, in healthy Chinese subjects. METHODS: Twenty-four subjects, all CYP2D6 extensive metabolizers (EM), were randomize...

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Autors principals: Cui, Yi M, Teng, Choo H, Pan, Alan X, Yuen, Eunice, Yeo, Kwee P, Zhou, Ying, Zhao, Xia, Long, Amanda J, Bangs, Mark E, Wise, Stephen D
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2007
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048549/
https://ncbi.nlm.nih.gov/pubmed/17610534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02912.x
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