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RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins

Pre-mRNA splicing requires a large number of RNA-binding proteins that have one or more RNA-recognition motifs (RRMs). Among these is the SR protein family, whose members are essential for splicing and are able to commit pre-mRNAs to the splicing pathway with overlapping but distinct substrate speci...

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Detalhes bibliográficos
Main Authors: Chandler, Sharon D., Mayeda, Akila, Yeakley, Joanne M., Krainer, Adrian R., Fu, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20485/
https://ncbi.nlm.nih.gov/pubmed/9108022
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