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The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules

BACKGROUND: Impairment of cilia and flagella function underlies a growing number of human genetic diseases. Mutations in hydin in hy3 mice cause lethal communicating hydrocephalus with early onset. Hydin was recently identified as an axonemal protein; however, its function is as yet unknown. RESULTS...

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Bibliografiske detaljer
Main Authors: Dawe, Helen R, Shaw, Michael K, Farr, Helen, Gull, Keith
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048497/
https://ncbi.nlm.nih.gov/pubmed/17683645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-5-33
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