Src regulated by C-terminal phosphorylation is monomeric

The activity of the c-Src protein tyrosine kinase is regulated by phosphorylation of a tyrosine residue (Tyr-527) in the C-terminal tail of the molecule. Phosphorylation of Tyr-527 promotes association of the tail with the SH2 domain and a concomitant reduction of the enzymatic activity of Src. We a...

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Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Weijland, Albert, Williams, John C., Neubauer, Gitte, Courtneidge, Sara A., Wierenga, Rik K., Superti-Furga, Giulio
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 1997
Ämnen:	Biological Sciences
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3590
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