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Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab

OspA (outer surface protein A) is an abundant immunogenic lipoprotein of the Lyme disease spirochete Borrelia burgdorferi. The crystal structure of a soluble recombinant form of OspA was solved in a complex with the Fab fragment of mouse monoclonal antibody 184.1 and refined to a resolution of 1.9 Å...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Li, Hong, Dunn, John J., Luft, Benjamin J., Lawson, Catherine L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108020/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3584
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