Overexpression of the MarA positive regulator is sufficient to confer multiple antibiotic resistance in Escherichia coli.

A genetic approach was undertaken to identify normal bacterial genes whose products function to limit the effective concentration of antibiotics. In this approach, a multicopy plasmid library containing cloned Escherichia coli chromosomal sequences was screened for transformants that showed increase...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Gambino, L, Gracheck, S J, Miller, P F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8491710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.10.2888-2894.1993
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