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Gemfibrozil, a Lipid-lowering Drug, Inhibits the Induction of Nitric-oxide Synthase in Human Astrocytes

Gemfibrozil, a lipid-lowering drug, inhibited cytokine-induced production of NO and the expression of inducible nitric-oxide synthase (iNOS) in human U373MG astroglial cells and primary astrocytes. Similar to gemfibrozil, clofibrate, another fibrate drug, also inhibited the expression of iNOS. Inhib...

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Autori principali: Pahan, Kalipada, Jana, Malabendu, Liu, Xiaojuan, Taylor, Bradley S., Wood, Charles, Fischer, Susan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045648/
https://ncbi.nlm.nih.gov/pubmed/12244038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M200250200
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