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When it comes to opiates, just say NO
Repeated use of opiate analgesic drugs such as morphine for the relief of chronic pain may result in the development of opiate tolerance and dependence, leading to a narrowing of the drug’s therapeutic index and increased side effects. Previous preclinical work has shown that interruption of a signa...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045628/ https://ncbi.nlm.nih.gov/pubmed/17975665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34035 |
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