Characterization of the Lactococcus lactis nisin A operon genes nisP, encoding a subtilisin-like serine protease involved in precursor processing, and nisR, encoding a regulatory protein involved in nisin biosynthesis.

Biosynthesis of the lantibiotic peptide nisin by Lactococcus lactis NIZO R5 relies on the presence of the conjugative transposon Tn5276 in the chromosome. A 12-kb DNA fragment of Tn5276 including the nisA gene and about 10 kb of downstream DNA was cloned in L. lactis, resulting in the production of...

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הוצא לאור ב:	J Bacteriol
Principais autores:	van der Meer, J R, Polman, J, Beerthuyzen, M M, Siezen, R J, Kuipers, O P, De Vos, W M
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1993
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8478324/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.9.2578-2588.1993
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