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Innate Recognition Network Driving Herpes Simplex Virus-Induced Corneal Immunopathology: Role of the Toll Pathway in Early Inflammatory Events in Stromal Keratitis

Ocular infection with herpes simplex virus (HSV) sets off an array of events that succeed in clearing virus from the cornea but leaves the tissue with a CD4(+) T-cell-orchestrated chronic inflammatory lesion that impairs vision. We demonstrate that Toll-like receptor (TLR) signaling forms a part of...

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Autors principals: Sarangi, Pranita P., Kim, Bumseok, Kurt-Jones, Evelyn, Rouse, Barry T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045562/
https://ncbi.nlm.nih.gov/pubmed/17686871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01008-07
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