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Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement.

Streptomyces avermitilis produces a group of glycosylated, methylated macrocyclic lactones, the avermectins, which have potent anthelmintic activity. A homologous recombination strategy termed gene cluster displacement was used to construct Neor deletion strains with defined endpoints and to clone t...

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Xehetasun bibliografikoak
Argitaratua izan da:J Bacteriol
Egile Nagusiak: MacNeil, T, Gewain, K M, MacNeil, D J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1993
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8478321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.9.2552-2563.1993
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