Alterations in Receptor Binding Properties of Recent Human Influenza H3N2 Viruses Are Associated with Reduced Natural Killer Cell Lysis of Infected Cells

Natural killer (NK) cell recognition of influenza virus-infected cells involves hemagglutinin (HA) binding to sialic acid (SA) on activating NK receptors. SA also acts as a receptor for the binding of influenza virus to its target host cells. The SA binding properties of H3N2 influenza viruses have...

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Main Authors: Owen, Rachel E., Yamada, Eriko, Thompson, Catherine I., Phillipson, Louisa J., Thompson, Clare, Taylor, Elizabeth, Zambon, Maria, Osborn, Helen M. I., Barclay, Wendy S., Borrow, Persephone
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045558/
https://ncbi.nlm.nih.gov/pubmed/17670834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01217-07
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