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West Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKR

Cells carry a variety of molecules, referred to as pathogen recognition receptors (PRRs), which are able to sense invading pathogens. Interaction of PRRs with viral compounds instigates a signaling pathway(s), resulting in the activation of genes, including those for type I interferon (IFN), which a...

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Detalhes bibliográficos
Main Authors: Gilfoy, Felicia D., Mason, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045557/
https://ncbi.nlm.nih.gov/pubmed/17686861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00446-07
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