Enhancement of Murine Coronavirus Replication by Severe Acute Respiratory Syndrome Coronavirus Protein 6 Requires the N-Terminal Hydrophobic Region but Not C-Terminal Sorting Motifs

Severe acute respiratory syndrome coronavirus encodes several accessory proteins of unknown function. We previously showed that one such protein, encoded by ORF6, enhanced the growth of mouse hepatitis virus in tissue culture cells and in mice. Protein 6 consists of an N-terminal hydrophobic peptide...

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Main Authors: Netland, Jason, Ferraro, Debra, Pewe, Lecia, Olivares, Heidi, Gallagher, Thomas, Perlman, Stanley
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045524/
https://ncbi.nlm.nih.gov/pubmed/17670827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01308-07
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