Although Macrophage-Tropic Simian/Human Immunodeficiency Viruses Can Exhibit a Range of Pathogenic Phenotypes, a Majority of Isolates Induce No Clinical Disease in Immunocompetent Macaques

Unlike prototypical lentiviruses like visna and caprine arthritis-encephalitis viruses, which are mainly macrophage tropic (M-tropic), primate lentiviruses primarily target CD4(+) T lymphocytes. We previously reported that during the late phase of highly pathogenic chimeric simian/human immunodefici...

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Autores principales: Igarashi, Tatsuhiko, Donau, Olivia K., Imamichi, Hiromi, Nishimura, Yoshiaki, Theodore, Theodore S., Iyengar, Ranjini, Erb, Christopher, Buckler-White, Alicia, Buckler, Charles E., Martin, Malcolm A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045473/
https://ncbi.nlm.nih.gov/pubmed/17626082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00517-07
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