Epstein-Barr Virus Exploits BSAP/Pax5 To Achieve the B-Cell Specificity of Its Growth-Transforming Program

Epstein-Barr virus (EBV) can infect various cell types but limits its classical growth-transforming function to B lymphocytes, the cells in which it persists in vivo. Transformation initiates with the activation of Wp, a promoter present as tandemly repeated copies in the viral genome. Assays with s...

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Autors principals: Tierney, Rosemary, Nagra, Jasdeep, Hutchings, Isabel, Shannon-Lowe, Claire, Altmann, Markus, Hammerschmidt, Wolfgang, Rickinson, Alan, Bell, Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045388/
https://ncbi.nlm.nih.gov/pubmed/17626071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00358-07
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