Altered adenosine-to-inosine RNA editing in human cancer

Adenosine-to-inosine (A-to-I) RNA editing was recently shown to be abundant in the human transcriptome, affecting thousands of genes. Employing a bioinformatic approach, we identified significant global hypoediting of Alu repetitive elements in brain, prostate, lung, kidney, and testis tumors. Exper...

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Autori principali: Paz, Nurit, Levanon, Erez Y., Amariglio, Ninette, Heimberger, Amy B., Ram, Zvi, Constantini, Shlomi, Barbash, Zohar S., Adamsky, Konstantin, Safran, Michal, Hirschberg, Avi, Krupsky, Meir, Ben-Dov, Issachar, Cazacu, Simona, Mikkelsen, Tom, Brodie, Chaya, Eisenberg, Eli, Rechavi, Gideon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045141/
https://ncbi.nlm.nih.gov/pubmed/17908822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6493107
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