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Inhibition by purines of the inotropic action of isoprenaline in rat atria.

The effects of a series of adenosine derivatives were examined on the catecholamine-stimulated electrically-driven rat left atrium in vitro. All the purines tested reduced the positive inotropic action of isoprenaline, 0.1 microM, with the potency order: L-N6-phenlylisopropyladenosine (L-PIA) greate...

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Autors principals: Hughes, P. R., Stone, T. W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1983
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044977/
https://ncbi.nlm.nih.gov/pubmed/6317127
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