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Importance of physico-chemical properties in determining the kinetics of the effects of Class I antiarrhythmic drugs on maximum rate of depolarization in guinea-pig ventricle.

The effects of Class I antiarrhythmic drugs on the maximum rate of depolarization (Vmax) of guinea-pig ventricular action potentials were studied by standard microelectrode techniques. The ability of seven different drugs to depress Vmax in unstimulated tissue ('resting block') was found t...

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Hlavní autor: Campbell, T. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044966/
https://ncbi.nlm.nih.gov/pubmed/6652373
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