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The effects of chloroquine and other weak bases on the accumulation and efflux of digoxin and ouabain in HeLa cells.

We have studied the effects of the weak bases chloroquine, NH4Cl and amantadine on the handling of certain cardiac glycosides by HeLa cells. When these weak bases are applied acutely to HeLa cells they have only minor effects on the binding of cardiac glycosides to the sodium pumps and on the recove...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Griffiths, N., Lamb, J. F., Ogden, P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1983
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044946/
https://ncbi.nlm.nih.gov/pubmed/6652360
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