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Antinociceptive action of nicotine and its methiodide derivatives in mice and rats.

Three quaternary methiodides of nicotine were prepared and tested for antinociceptive activity in the mouse tail-flick, mouse phenylquinone and rat tail-flick tests. Following peripheral administration, all three methiodides were inactive in the mouse and rat tail-flick procedures, whereas nicotine...

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Detalhes bibliográficos
Main Authors: Aceto, M. D., Awaya, H., Martin, B. R., May, E. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044943/
https://ncbi.nlm.nih.gov/pubmed/6140048
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