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Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases

DNA glycosylases catalyze the excision of chemically modified bases from DNA. Although most glycosylases are specific to a particular base, the 3-methyladenine (m(3)A) DNA glycosylases include both highly specific enzymes acting on a single modified base, and enzymes with broader specificity for alk...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Eichman, Brandt F., O’Rourke, Eyleen J., Radicella, J.Pablo, Ellenberger, Tom
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204488/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg505
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