Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat.

1 We investigated the effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive ortho isomer on arachidonic acid metabolism and pathophysiological sequelae of endotoxic shock. In vehicle-treated rats, 30 min after intravenous S. enteritidis endotoxin (15 mg/kg), plasma iTxB2...

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Main Authors: Anderegg, K., Anzeveno, P., Cook, J. A., Halushka, P. V., McCarthy, J., Wagner, E., Wise, W. C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1983
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044743/
https://ncbi.nlm.nih.gov/pubmed/6687819
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