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The antinociceptive action of etorphine in the dorsal horn is due to a direct spinal action and not to activation of descending inhibition.

1--Etorphine, microinjected into the brainstem or administered intravenously, inhibited the firing of dorsal horn neurones to noxious heat in spinal or non-spinal anaesthetized cats and in decerebrate, non-anaesthetized cats with intact spinal cords. 2--Small doses of etorphine sometimes caused faci...

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Détails bibliographiques
Auteurs principaux: Clark, S. L., Ryall, R. W.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044707/
https://ncbi.nlm.nih.gov/pubmed/6338986
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