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Zinc fingers can act as Zn(2+) sensors to regulate transcriptional activation domain function

The yeast Zap1 transcription factor controls the expression of genes involved in zinc accumulation and storage. Zap1 is active in zinc-limited cells and repressed in replete cells. Zap1 has two activation domains, AD1 and AD2, which are both regulated by zinc. AD2 function was mapped to a region con...

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Detalhes bibliográficos
Main Authors: Bird, Amanda J., McCall, Keith, Kramer, Michelle, Blankman, Elizabeth, Winge, Dennis R., Eide, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC204467/
https://ncbi.nlm.nih.gov/pubmed/14517251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg484
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