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Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate.

1 Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and noncompetitively inhibits stimulated human platelet adenylate cyclase; these two effects are mediated by the same ADP receptor, at which adenosine 5'-triphosphate (ATP) is a competitive antagonist. 2 Two ADP analogues,...

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Autors principals: Cusack, N. J., Hourani, S. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044602/
https://ncbi.nlm.nih.gov/pubmed/7139191
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