Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells

Cystic fibrosis (CF) is an autosomal recessive disorder, the most common lethal genetic disease in Caucasians. Respiratory disease is the major cause of morbidity and mortality. Indeed, 95% of CF patients die of respiratory failure. Pseudomonas aeruginosa, an opportunistic pathogen, chronically infe...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Li, Jian-Dong, Feng, Weijun, Gallup, Marianne, Kim, Jae-Ho, Gum, James, Kim, Young, Basbaum, Carol
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.10.5718
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