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Substance P increases hypothalamic blood flow via an indirect adrenergic-cholinergic interaction.

1 Hypothalamic blood flow (HBF) was measured in conscious rabbits by the 133xenon washout technique. 2 Substance P in a dose of 50 or 500 ng increases HBF while 5 ng is without effect. 3 Cholinoceptor blockade, with either atropine or mecamylamine abolishes the vasodilator effect of substance P. 4 C...

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Detalhes bibliográficos
Main Authors: Klugman, K. P., Lembeck, F., Markowitz, S., Mitchell, G., Rosendorff, C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044472/
https://ncbi.nlm.nih.gov/pubmed/6162500
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