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Interaction between synthetic analogues of quinoxaline antibiotics and nucleic acids: role of the disulphide cross-bridge and D-amino acid centres in des-N-tetramethyl-triostin A.

1 [Ala3, Ala7] TANDEM is an analogue of des-N-tetramethyl-triostin A (TANDEM) in which both L-Cys residues of the octapeptide ring are replaced by L-Ala; accordingly it lacks the disulphide cross-bridge which limits the conformational flexibility of TANDEM. 2 In [L-Ser1] TANDEM the configuration of...

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Bibliografische gegevens
Hoofdauteurs: Fox, K. R., Olsen, R. K., Waring, M. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1980
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044367/
https://ncbi.nlm.nih.gov/pubmed/7426829
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