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The relationship between nerve terminal adenosine triphosphatases and neurotransmitter release: as determined by the use of antidepressant and other CNS-active drugs.

1 The role of adenosine triphosphatases (ATPases) in neurotransmitter release was studied using nerve terminals (synaptosomes) prepared from rat cerebral cortex as a model. 2 Amitriptyline, nortriptyline, protriptyline, desipramine and imipramine were found to inhibit ATPases at concentrations of 10...

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Autors principals: Gilbert, J. C., Wyllie, M. G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1980
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044255/
https://ncbi.nlm.nih.gov/pubmed/6108138
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