A study of some propranolol analogues for selective beta-adrenoceptor antagonism using A2 values on isolated trachea and atria from guinea-pig.

1 PA2 values for beta-adrenoceptor antagonists were obtained on isolated preparations of guinea-pig trachea (intrinsic tone) and atria (rate), with isoprenaline, noradrenaline (beta 1-selective) and fenoterol (beta 2-selective) as agonists. Uptake mechanisms and alpha-adrenoceptors were inhibited. T...

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Hauptverfasser: O'Donnell, S. R., Walduck, K., Wanstall, J. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1980
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044231/
https://ncbi.nlm.nih.gov/pubmed/6103723
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