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Antagonism by fenamates of prostaglandin action in guinea-pig and human alimentary muscle.

1 Low concentrations of meclofenamate, flufenamate or mefenamate had little effect on contractions in response to acetylcholine in any tissue studied. 2 Sodium meclofenamate potently antagonized contractions of guinea-pig ileum longitudinal muscle to prostaglandin E2 (PGE2), PGF2 alpha or PGD2. 3 In...

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Bibliographic Details
Main Authors: Bennett, A., Pratt, D., Sanger, G. J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044210/
https://ncbi.nlm.nih.gov/pubmed/7052332
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