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Dipyridamole: a potent stimulator of prostacyclin (PGI2) biosynthesis.

1 Dipyridamole (0.01 to 0.75 mM) increased prostacyclin (PGI2) biosynthesis from tritiated arachidonic acid in rat stomach fundus homogenates by 21 to 350%. The transformation of prostaglandin H2 (PGH2) to PGI2 by a microsomal fraction of pig aorta was stimulated by dipyridamole at 0.1 M by 63%. 2 I...

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Autors principals: Blass, K. E., Block, H. U., Förster, W., Pönicke, K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1980
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044099/
https://ncbi.nlm.nih.gov/pubmed/6766769
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