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The effects of ions on the binding of agonists and antagonists to muscarinic receptors.

1 There are no selective effects of Na+, K+, Ca2+, Mg2+ or Cl- on the binding of antagonists or agonists to muscarinic receptors in rat brain. A decrease in affinity related to ionic strength is found for all these ions. 2 Larger effects were produced by T1+, La3+, and some transition metal ions.

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Bibliografiske detaljer
Main Authors: Birdsall, N. J., Burgen, A. S., Hulme, E. C., Wells, J. W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1979
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043948/
https://ncbi.nlm.nih.gov/pubmed/497538
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