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Functional antagonism as a means of determining dissociation constants and relative efficacies of sympathomimetic amines in guinea-pig isolated atria.

1 The positive inotropic and chronotropic responses to sympathomimetic amines were examined in guinea-pig isolated atria. 2 The order of potency measured from EC50 values was isoprenaline greater than orciprenaline greater than salbutamol greater than or equal to fenoterol greater than terbutaline....

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Autors principals: Broadley, K. J., Nicholson, C. D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043687/
https://ncbi.nlm.nih.gov/pubmed/526709
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