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Humanizing the yeast telomerase template

Saccharomyces cerevisiae contains an irregular telomere sequence (TG(1–3))(n), which differs from the regular repeat (TTAGGG)(n) found at the telomeres of higher organisms including humans. We have modified the entire 16-nt template region of the S. cerevisiae telomerase RNA gene (TLC1) to produce (...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Henning, Karla A., Moskowitz, Naomi, Ashlock, Melissa A., Liu, Pu P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.10.5667
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