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The inhibitory effects of presynaptic alpha-adrenoceptor agonists on contractions of guinea-pig ileum and mouse vas deferens in the morphine-dependent and withdrawn states produced in vitro.

1 Isolated ilea from guinea-pigs implanted with morphine pellets were stimulated coaxially, either with or without morphine present in the bath fluid, and the longitudinal contractions recorded. 2 In the absence of morphine the inhibitory effects of the presynaptic alpha-adrenoceptor agonists, cloni...

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Autors principals: Gillan, M. G., Kosterlitz, H. W., Robson, L. E., Waterfield, A. A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043589/
https://ncbi.nlm.nih.gov/pubmed/37965
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