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The Chromosomal Passenger Complex Controls Spindle Checkpoint Function Independent from Its Role in Correcting Microtubule–Kinetochore Interactions

The chromosomal passenger complex (CPC) is a critical regulator of chromosome segregation during mitosis by correcting nonbipolar microtubule-kinetochore interactions. By severing these interactions, the CPC is thought to create unattached kinetochores that are subsequently sensed by the spindle ass...

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Autori principali: Vader, Gerben, Cruijsen, Carin W.A., van Harn, Tanja, Vromans, Martijn J.M., Medema, René H., Lens, Susanne M.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043551/
https://ncbi.nlm.nih.gov/pubmed/17699588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0328
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